Classic ASP MS Access on IIS 8.5 on Window Server 2012 R2

Receiving access denied errors when accessing a website with .mdb file.

HKLM\SOFTWARE\wow6432node\microsoft\jet\4.0\engines access denied when procmon is running.

HKLM\SOFTWARE\wow6432node\ODBC.INI

HKLM\SOFTWARE\wow6432node\ODBC

HKLM\SOFTWARE\wow6432node\ODBC\Temporary(volatile) Jet DSN for process 0x8a4 Thread 0x131c DBC 0x22060064 Jet

also seeing D:\inetpub\xyz\database\xyz.mdb and D:\inetpub\xyz\database\xyz.ld bbuffer overflow errors.